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- Title
Unlocking the DEAD-box: a key to cryptococcal virulence?
- Authors
Heung, Lena J; Del Poeta, Maurizio
- Abstract
The DEAD-box RNA helicases are enzymes involved in many critical aspects of RNA metabolism within both eukaryotic and prokaryotic organisms. Several studies have shown that these proteins may have important functions in mediating microbial pathogenesis. A new study in this issue of the JCI identifies the first DEAD-box RNA helicase in the pathogenic fungus Cryptococcus neoformans and proposes novel roles for this family of proteins in the development and progression of cryptococcosis.
- Publication
The Journal of clinical investigation, 2005, Vol 115, Issue 3, p593
- ISSN
0021-9738
- Publication type
Journal Article
- DOI
10.1172/JCI24508