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- Title
The application of biofilm science to the study and control of chronic bacterial infections.
- Authors
Costerton, William; Veeh, Richard; Shirtliff, Mark; Pasmore, Mark; Post, Christopher; Ehrlich, Garth
- Abstract
Unequivocal direct observations have established that the bacteria that cause device-related and other chronic infections grow in matrix-enclosed biofilms. The diagnostic and therapeutic strategies that have served us so well in the partial eradication of acute epidemic bacterial diseases have not yielded accurate data or favorable outcomes when applied to these biofilm diseases. We discuss the potential benefits of the application of the new methods and concepts developed by biofilm science and engineering to the clinical management of infectious diseases.
- Publication
The Journal of clinical investigation, 2003, Vol 112, Issue 10, p1466
- ISSN
0021-9738
- Publication type
Journal Article
- DOI
10.1172/JCI20365