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- Title
Genetic variations of the NR3A subunit of the NMDA receptor modulate prefrontal cerebral activity in humans.
- Authors
Gallinat, Jürgen; Götz, Thomas; Kalus, Peter; Bajbouj, Malek; Sander, Thomas; Winterer, Georg
- Abstract
Recently, a novel N-methyl-D-aspartate (NMDA) receptor subunit, NR3A, has been discovered in the brain. This subunit decreases NMDA receptor activity by modulating the calcium permeability of the receptor channel and current density in cortical cells. Because the NR3A is expressed in the human prefrontal cortex, we hypothesized that genetic variations of the NR3A subunit modulate prefrontal activation.
- Publication
Journal of cognitive neuroscience, 2007, Vol 19, Issue 1, p59
- ISSN
0898-929X
- Publication type
Journal Article
- DOI
10.1162/jocn.2007.19.1.59