We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Methods of Cell Purification: A Critical Juncture for Laboratory Research and Translational Science.
- Authors
Amos, Peter J.; Cagavi Bozkulak, Esra; Qyang, Yibing
- Abstract
Research in cell biology and the development of translational technologies are driven by competition, public expectations, and regulatory oversight, putting these fields at a critical juncture. Success in these fields is quickly becoming dependent on the ability of researchers to identify and isolate specific cell populations from heterogeneous mixtures accurately and efficiently. Many methods for cell purification have been developed, and each has advantages and disadvantages that must be considered in light of the intended application. Current cell separation strategies make use of surface proteins, genetic expression, and physics to isolate specific cells by phenotypic traits. Cell purification is also dependent on the cellular reagents available for use and the intended application, as these factors may preclude certain mechanisms used in the processes of labeling and sorting cells. Copyright © 2011 S. Karger AG, Basel
- Publication
Cells Tissues Organs, 2011, Vol 195, Issue 1/2, p26
- ISSN
1422-6405
- Publication type
Academic Journal
- DOI
10.1159/000331390