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- Title
I-CLIP: improved stratification of advanced hepatocellular carcinoma patients by integrating plasma IGF-1 into CLIP score.
- Authors
Kaseb, Ahmed O; Abbruzzese, James L; Vauthey, Jean-Nicolas; Aloia, Thomas A; Abdalla, Eddie K; Hassan, Manal M; Lin, E; Xiao, Lianchun; El-Deeb, Adel S; Rashid, Asif; Morris, Jeffrey S
- Abstract
Improving the prognostic stratification of unresectable hepatocellular carcinoma (HCC) patients is critically needed. Since patients' survival is closely linked to the severity of the underlying liver disease, and insulin-like growth factor-1 (IGF-1) is produced predominantly in the liver, we hypothesized that IGF-1 may correlate with patients' survival and hence improve the prognostic ability of the Cancer of the Liver Italian Program (CLIP) score.
- Publication
Oncology, 2011, Vol 80, Issue 5-6, p373
- ISSN
1423-0232
- Publication type
Journal Article
- DOI
10.1159/000329040