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- Title
Folate and homocysteine in the cerebrospinal fluid of patients with Alzheimer's disease or dementia: a case control study.
- Authors
Smach, Mohamed Ali; Jacob, Nelly; Golmard, Jean-Louis; Charfeddine, Bassem; Lammouchi, Turkia; Ben Othman, Leila; Dridi, Hedi; Bennamou, Soufien; Limem, Khalifa
- Abstract
Amyloid deposition in the brain is an early event in Alzheimer's disease (AD), but a dysfunction of the blood-brain barrier or a disturbance in the metabolism of folate and homocysteine (Hcy) may affect the development of dementia. We investigated if the concentrations of folate and Hcy would be modified in cerebrospinal fluid (CSF) of clinically diagnosed AD patients.
- Publication
European neurology, 2011, Vol 65, Issue 5, p270
- ISSN
1421-9913
- Publication type
Journal Article
- DOI
10.1159/000326301