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- Title
Blind verification of elevated platelet autoantibodies in serum of schizophrenic patients--part II: adult subjects.
- Authors
Spivak, Baruch; Schechtman, Mila; Schonherz-Pine, Yael; Blumensohn, Rachel; Mostovoy, Susanna; Amital, Daniela; Deckmann, Michael; Weizman, Abraham; Shinitzky, Meir
- Abstract
In our preceding study, we assayed in a blind fashion the blood sera of young normal subjects and schizophrenic patients for levels of platelet autoantibodies (PAA). The recorded PAA titers of the schizophrenic patients were significantly higher than those of the normal subjects. This observation has lent support to this test being used as an objective evaluation of schizophrenia in young subjects in the future. In addition, this finding strongly suggested that the etiology of a distinct group of sufferers of this disorder could have originated from an autoimmune reaction against platelets which can, under certain conditions, cross-react with brain tissue.
- Publication
Neuropsychobiology, 2009, Vol 60, Issue 1, p49
- ISSN
1423-0224
- Publication type
Journal Article
- DOI
10.1159/000235802