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- Title
Association analysis of genes involved in the maintenance of the integrity of the extracellular matrix with intracranial aneurysms in a Japanese cohort.
- Authors
Ruigrok, Ynte M; Rinkel, Gabriel J E; Wijmenga, Cisca; Kasuya, Hidetoshi; Tajima, Atsushi; Takahashi, Tomoko; Hata, Akira; Inoue, Ituro; Krischek, Boris
- Abstract
An association between versican (CSPG2), perlecan (HSPG2), fibrillin 2 (FBN2) and collagen 4A1 (COL4A1) gene variants and intracranial aneurysms (IA) has been reported in 2 studies analyzing Dutch IA patients. The aim of this study was to verify these associations in a Japanese IA population. In addition, a meta-analysis on the association of these genes and IA for the combined Dutch and Japanese populations was performed.
- Publication
Cerebrovascular diseases (Basel, Switzerland), 2009, Vol 28, Issue 2, p131
- ISSN
1421-9786
- Publication type
Journal Article
- DOI
10.1159/000223438