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- Title
Conditional tests for localizing trait genes.
- Authors
Di, Yanming; Thompson, Elizabeth A
- Abstract
With pedigree data, genetic linkage can be detected using inheritance vector tests, which explore the discrepancy between the posterior distribution of the inheritance vectors given observed trait values and the prior distribution of the inheritance vectors. In this paper, we propose conditional inheritance vector tests for linkage localization. These conditional tests can also be used to detect additional linkage signals in the presence of previously detected causal genes.
- Publication
Human heredity, 2009, Vol 68, Issue 2, p139
- ISSN
1423-0062
- Publication type
Journal Article
- DOI
10.1159/000218112