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- Title
Impact of intravenous loop diuretics on outcomes of patients hospitalized with acute decompensated heart failure: insights from the ADHERE registry.
- Authors
Peacock, W Franklin; Costanzo, Maria Rosa; De Marco, Teresa; Lopatin, Margarita; Wynne, Janet; Mills, Roger M; Emerman, Charles L; ADHERE Scientific Advisory Committee and Investigators
- Abstract
The optimal use of diuretics in decompensated heart failure remains uncertain. We analyzed data from the ADHERE registry to look at the impact of diuretic dosing. 62,866 patients receiving <160 mg and 19,674 patients > or =160 mg of furosemide were analyzed. The patients receiving the lower doses had a lower risk for in-hospital mortality, ICU stay, prolonged hospitalization, or adverse renal effects. These findings suggest that future studies should evaluate strategies for minimizing exposure to high doses of diuretics.
- Publication
Cardiology, 2009, Vol 113, Issue 1, p12
- ISSN
1421-9751
- Publication type
Journal Article
- DOI
10.1159/000164149