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- Title
Association of the homeobox transcription factor gene ENGRAILED 2 with autistic disorder in Chinese children.
- Authors
Yang, Pinchen; Lung, For-Wey; Jong, Yuh-Jyh; Hsieh, Hsin-Yi; Liang, Chung-Ling; Juo, Suh-Hang Hank
- Abstract
Autism is a neurodevelopmental disorder with a strong genetic component. Previous studies have mapped the disease to chromosome 7q, where the homeobox transcription factor ENGRAILED 2 (EN2) gene is located. EN2 is specifically involved in patterning the region that gives rise to the cerebellum. In the present work, we carried out a case-control study to determine whether 2 intronic single-nucleotide polymorphisms (SNPs) of EN2 are a susceptibility to autism in a Han Chinese population.
- Publication
Neuropsychobiology, 2008, Vol 57, Issue 1-2, p3
- ISSN
1423-0224
- Publication type
Journal Article
- DOI
10.1159/000123115