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Title
Cytochrome p450 enzyme polymorphism frequency in indigenous and native american populations: a systematic review.
Authors
Jaja, Cheedy; Burke, Wylie; Thummel, Ken; Edwards, Karen; Veenstra, David L
Abstract
The purpose of our study was to evaluate the evidence on the prevalence of cytochrome P450 enzyme polymorphisms as potential genetic factors influencing drug efficacy and safety in the indigenous populations of the American hemispheres.