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Title
Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer.
Authors
Slaby, O; Svoboda, M; Fabian, P; Smerdova, T; Knoflickova, D; Bednarikova, M; Nenutil, R; Vyzula, R
Abstract
Development and metastases of colorectal cancer (CRC) are characterized by multiple genetic alterations. MicroRNAs (miRNAs) are endogenously expressed regulatory noncoding RNAs. Previous, mainly preclinical studies showed altered expression levels of several miRNAs in CRC.