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- Title
House dust and storage mite extracts influence skin keratinocyte and fibroblast function.
- Authors
Arlian, Larry G; Morgan, Marjorie S; Peterson, Kevin T
- Abstract
The bodies of allergy-causing dust and storage mites likely contain many bioreactive molecules, including some that are allergenic. These molecules may penetrate the epidermis and dermis of the skin. However, little is known about the effects that most of the molecules from mites have on the function of cells in the skin, the overall inflammatory and immune reactions and the manifestation of allergic disease. The purpose of this research was to determine the response of cultured skin cells (keratinocytes and fibroblasts) to extracts of house dust and storage mites.
- Publication
International archives of allergy and immunology, 2008, Vol 145, Issue 1, p33
- ISSN
1423-0097
- Publication type
Journal Article
- DOI
10.1159/000107464