We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Prolonged treatment with low-dose intravenous pulse cyclophosphamide may reduce rate of relapse in ANCA-associated vasculitis.
- Authors
Dhaygude, Ajay; Griffith, Megan; Cairns, Thomas; McLean, Adam; Palmer, Andrew; Taube, David
- Abstract
Cyclophosphamide has transformed the outcome of ANCA-associated vasculitis, but it is highly toxic. Recent studies have suggested that pulsed intravenous cyclophosphamide (pCyc) is an effective alternative with less complications, but may lead to an increased rate of relapse. However, these studies used relatively short courses of treatment with cyclophosphamide. In this study we used a prolonged course of low-dose intravenous cyclophosphamide for 18-24 months for ANCA-associated vasculitis, evaluated the effectiveness of pCyc and analysed the outcome of a prolonged treatment on the rate of relapse.
- Publication
Nephron. Clinical practice, 2004, Vol 97, Issue 4, pc154
- ISSN
1660-2110
- Publication type
Journal Article
- DOI
10.1159/000079175