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- Title
Characterization of a new TSPY gene family member in Yq (TSPYq1).
- Authors
Ratti, A; Stuppia, L; Gatta, V; Fogh, I; Calabrese, G; Pizzuti, A; Palka, G
- Abstract
We investigated subinterval 6E on the human Y chromosome, a region frequently deleted in infertile males. YAC yOX17, mapped within subinterval 6E by STS-PCR, was analyzed for the presence of new genes. TSPYq1, a member of the TSPY multi-copy gene family, was isolated and characterized from a yOX17 cosmid subclone. PCR and FISH analysis performed on normal subjects and on patients with microdeletions of Yq suggested the presence of multiple copies of TSPY in Yq.
- Publication
Cytogenetics and cell genetics, 2000, Vol 88, Issue 1-2, p159
- ISSN
0301-0171
- Publication type
Journal Article
- DOI
10.1159/000015510