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- Title
Antioxidant therapy in nonalcoholic steatohepatitis.
- Authors
Al-Busafi, Said A; Bhat, Mamatha; Wong, Philip; Ghali, Peter; Deschenes, Marc
- Abstract
Nonalcoholic steatohepatitis (NASH) affects up to 3% of the North American population. It occurs as a manifestation of the insulin-resistant state and oxidative stress is thought to be a key component of its pathophysiology. Exercise and diet, which are the mainstay of therapy, are difficult to achieve and maintain with a disappointing long-term compliance record. There is growing literature on the potential for antioxidant therapy. The recent literature strongly suggests that vitamin E supplementation and other putative free radical scavengers and/or antioxidants are beneficial in improving biochemical and histological parameters in NASH.
- Publication
Hepatitis research and treatment, 2012, Vol 2012, p947575
- ISSN
2090-1372
- Publication type
Journal Article
- DOI
10.1155/2012/947575