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- Title
Neurological Disorders in Primary Sjögren's Syndrome.
- Authors
Tobón, Gabriel J; Pers, Jacques-Olivier; Devauchelle-Pensec, Valérie; Youinou, Pierre
- Abstract
Sjögren's syndrome is an autoimmune disease characterized by an autoimmune exocrinopathy involving mainly salivary and lacrimal glands. The histopathological hallmark is periductal lymphocytic infiltration of the exocrine glands, resulting in loss of their secretory function. Several systemic manifestations may be found in patients with Sjögren's syndrome including neurological disorders. Neurological involvement ranges from 0 to 70% among various series and may present with central nervous system and/or peripheral nervous system involvement. This paper endeavors to review the main clinical neurological manifestations in Sjögren syndrome, the physiopathology, and their therapeutic response.
- Publication
Autoimmune diseases, 2012, Vol 2012, p645967
- ISSN
2090-0430
- Publication type
Journal Article
- DOI
10.1155/2012/645967