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- Title
Kluyveromyces lactis: a suitable yeast model to study cellular defense mechanisms against hypoxia-induced oxidative stress.
- Authors
González Siso, M Isabel; Cerdán, M Esperanza
- Abstract
Studies about hypoxia-induced oxidative stress in human health disorders take advantage from the use of unicellular eukaryote models. A widely extended model is the fermentative yeast Saccharomyces cerevisiae. In this paper, we describe an overview of the molecular mechanisms induced by a decrease in oxygen availability and their interrelationship with the oxidative stress response in yeast. We focus on the differential characteristics between S. cerevisiae and the respiratory yeast Kluyveromyces lactis, a complementary emerging model, in reference to multicellular eukaryotes.
- Publication
Oxidative medicine and cellular longevity, 2012, Vol 2012, p634674
- ISSN
1942-0994
- Publication type
Journal Article
- DOI
10.1155/2012/634674