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- Title
A proteome reference map of the causative agent of melioidosis Burkholderia pseudomallei.
- Authors
Wongtrakoongate, Patompon; Roytrakul, Sittiruk; Yasothornsrikul, Sukkid; Tungpradabkul, Sumalee
- Abstract
Burkholderia pseudomallei is the etiologic agent of melioidosis. Using 2DE and MALDI-TOF MS, we report here a proteome reference map constructed from early stationary phase, a bacterial adaptation process. We identified 282 protein spots representing 220 ORFs; many of them have been implicated in bacterial pathogenesis. Up to 20% of identified ORFs belong to post-translational modification and stress responses. The proteome reference map will support future analysis of the bacterial gene and environmental regulation and facilitate comparative proteomics with its sibling species.
- Publication
Journal of biomedicine & biotechnology, 2011, Vol 2011, p530926
- ISSN
1110-7251
- Publication type
Journal Article
- DOI
10.1155/2011/530926