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- Title
The public health impact of prion diseases.
- Authors
Belay, Ermias D; Schonberger, Lawrence B
- Abstract
Several prion disease-related human health risks from an exogenous source can be identified in the United States, including the iatrogenic transmission of Creutzfeldt-Jakob disease (CJD), the possible occurrence of variant CJD (vCJD), and potential zoonotic transmission of chronic wasting disease (CWD). Although cross-species transmission of prion diseases seems to be limited by an apparent "species barrier," the occurrence of bovine spongiform encephalopathy (BSE) and its transmission to humans indicate that animal prion diseases can pose a significant public health risk. Recent reports of secondary person-to-person spread of vCJD via blood products and detection of vCJD transmission in a patient heterozygous at codon 129 further illustrate the potential public health impacts of BSE.
- Publication
Annual review of public health, 2005, Vol 26, p191
- ISSN
0163-7525
- Publication type
Journal Article
- DOI
10.1146/annurev.publhealth.26.021304.144536