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Title
Metabolism of fluorine-containing drugs.
Authors
Park, B K; Kitteringham, N R; O'Neill, P M
Abstract
This article reviews current knowledge of the metabolism of drugs that contain fluorine. The strategic value of fluorine substitution in drug design is discussed in terms of chemical structure and basic concepts in drug metabolism and drug toxicity.
Publication
Annual review of pharmacology and toxicology, 2001, Vol 41, p443