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- Title
Identification of trace element-containing proteins in genomic databases.
- Authors
Gladyshev, Vadim N; Kryukov, Gregory V; Fomenko, Dmitri E; Hatfield, Dolph L
- Abstract
Development of bioinformatics tools provided researchers with the ability to identify full sets of trace element-containing proteins in organisms for which complete genomic sequences are available. Recently, independent bioinformatics methods were used to identify all, or almost all, genes encoding selenocysteine-containing proteins in human, mouse, and Drosophila genomes, characterizing entire selenoproteomes in these organisms. It also should be possible to search for entire sets of other trace element-associated proteins, such as metal-containing proteins, although methods for their identification are still in development.
- Publication
Annual review of nutrition, 2004, Vol 24, p579
- ISSN
0199-9885
- Publication type
Journal Article
- DOI
10.1146/annurev.nutr.24.012003.132241