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- Title
Apoptosis in neural development and disease.
- Authors
Nijhawan, D; Honarpour, N; Wang, X
- Abstract
Cell death via apoptosis is a prominent feature in mammalian neural development. Recent studies into the basic mechanism of apoptosis have revealed biochemical pathways that control and execute apoptosis in mammalian cells. Protein factors in these pathways play important roles during development in regulating the balance between neuronal life and death. Additionally, mounting evidence indicates such pathways may also be activated during several neurodegenerative diseases, resulting in improper loss of neurons.
- Publication
Annual review of neuroscience, 2000, Vol 23, p73
- ISSN
0147-006X
- Publication type
Journal Article
- DOI
10.1146/annurev.neuro.23.1.73