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- Title
Bacterial chromosome segregation.
- Authors
Draper, Geoffrey C; Gober, James W
- Abstract
Recent studies have made great strides toward our understanding of the mechanisms of microbial chromosome segregation and partitioning. This review first describes the mechanisms that function to segregate newly replicated chromosomes, generating daughter molecules that are viable substrates for partitioning. Then experiments that address the mechanisms of bulk chromosome movement are summarized. Recent evidence indicates that a stationary DNA replication factory may be responsible for supplying the force necessary to move newly duplicated DNA toward the cell poles. Some factors contributing to the directionality of chromosome movement probably include centromere-like-binding proteins, DNA condensation proteins, and DNA translocation proteins.
- Publication
Annual review of microbiology, 2002, Vol 56, p567
- ISSN
0066-4227
- Publication type
Journal Article
- DOI
10.1146/annurev.micro.56.012302.160729