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- Title
Intercellular signaling during fruiting-body development of Myxococcus xanthus.
- Authors
Shimkets, L J
- Abstract
The myxobacterium Myxococcus xanthus has a life cycle that is dominated by social behavior. During vegetative growth, cells prey on other bacteria in large groups that have been likened to wolf packs. When faced with starvation, cells form a macroscopic fruiting body containing thousands of spores. The social systems that guide fruiting body development have been examined through the isolation of conditional developmental mutants that can be stimulated to develop in the presence of wild-type cells. Extracellular complementation is due to the transfer of soluble and cell contact-dependent intercellular signals. This review describes the current state of knowledge concerning cell-cell signaling during development.
- Publication
Annual review of microbiology, 1999, Vol 53, p525
- ISSN
0066-4227
- Publication type
Journal Article
- DOI
10.1146/annurev.micro.53.1.525