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- Title
The hypereosinophilic syndrome revisited.
- Authors
Roufosse, Florence; Cogan, Elie; Goldman, Michel
- Abstract
Clinical and biological features of patients with the idiopathic hypereosinophilic syndrome (HES) are heterogeneous. Recent evidence suggests at least two distinct underlying hematological disorders involving myeloid and lymphoid cells, respectively. We therefore suggest that the term idiopathic should be abandoned in the classification of HES. This review defines the "myeloproliferative" and "lymphocytic" variants of the HES and addresses the management of each variant, focusing on diagnosis and treatment of the newly identified lymphocytic variant.
- Publication
Annual review of medicine, 2003, Vol 54, p169
- ISSN
0066-4219
- Publication type
Journal Article
- DOI
10.1146/annurev.med.54.101601.152431