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- Title
Genetic control of retrovirus susceptibility in mammalian cells.
- Authors
Goff, Stephen P
- Abstract
Host cellular genes can have profound effects on retrovirus replication. Many of these genes encode restriction factors that block virus infection; others encode positive factors that are exploited by the viruses. Recently, a number of such genes have been cloned and characterized, bringing into sharper focus the mechanisms and pathways exploited by these viruses. The major host factors involved in the early phase of the viral life cycle are discussed.
- Publication
Annual review of genetics, 2004, Vol 38, p61
- ISSN
0066-4197
- Publication type
Journal Article
- DOI
10.1146/annurev.genet.38.072902.094136