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- Title
Cyclin-dependent kinases: engines, clocks, and microprocessors.
- Authors
Morgan, D O
- Abstract
Cyclin-dependent kinases (Cdks) play a well-established role in the regulation of the eukaryotic cell division cycle and have also been implicated in the control of gene transcription and other processes. Cdk activity is governed by a complex network of regulatory subunits and phosphorylation events whose precise effects on Cdk conformation have been revealed by recent crystallographic studies. In the cell, these regulatory mechanisms generate an interlinked series of Cdk oscillators that trigger the events of cell division.
- Publication
Annual review of cell and developmental biology, 1997, Vol 13, p261
- ISSN
1081-0706
- Publication type
Journal Article
- DOI
10.1146/annurev.cellbio.13.1.261