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- Title
Structure of proteins involved in synaptic vesicle fusion in neurons.
- Authors
Brunger, A T
- Abstract
The fusion of vesicles with target membranes is controlled by a complex network of protein-protein and protein-lipid interactions. Structures of the SNARE complex, synaptotagmin III, nSec1, domains of the NSF chaperone and its adaptor SNAP, and Rab3 and some of its effectors provide the framework for developing molecular models of vesicle fusion and for designing experiments to test these models.
- Publication
Annual review of biophysics and biomolecular structure, 2001, Vol 30, p157
- ISSN
1056-8700
- Publication type
Journal Article
- DOI
10.1146/annurev.biophys.30.1.157