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- Title
Biophysical and phenomenological models of multiple spike interactions in spike-timing dependent plasticity.
- Authors
Badoual, Mathilde; Zou, Quan; Davison, Andrew P; Rudolph, Michael; Bal, Thierry; Frégnac, Yves; Destexhe, Alain
- Abstract
Spike-timing dependent plasticity (STDP) is a form of associative synaptic modification which depends on the respective timing of pre- and post-synaptic spikes. The biophysical mechanisms underlying this form of plasticity are currently not known. We present here a biophysical model which captures the characteristics of STDP, such as its frequency dependency, and the effects of spike pair or spike triplet interactions. We also make links with other well-known plasticity rules. A simplified phenomenological model is also derived, which should be useful for fast numerical simulation and analytical investigation of the impact of STDP at the network level.
- Publication
International journal of neural systems, 2006, Vol 16, Issue 2, p79
- ISSN
0129-0657
- Publication type
Journal Article
- DOI
10.1142/S0129065706000524