We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Regulation of arachidonic acid availability for eicosanoid production.
- Authors
Leslie, Christina C
- Abstract
Mammalian cells have developed specific pathways for the incorporation, remodeling, and release of arachidonic acid. Acyltransferase and transacylase pathways function to regulate the levels of esterified arachidonic acid in specific phospholipid pools. There are several distinct, differentially regulated phospholipases A2 in cells that mediate agonist-induced release of arachidonic acid. These pathways are important in controlling cellular levels of free arachidonic acid. Both arachidonic acid and its oxygenated metabolites are potent bioactive mediators that regulate a myriad of physiological and pathophysiological processes.
- Publication
Biochemistry and cell biology = Biochimie et biologie cellulaire, 2004, Vol 82, Issue 1, p1
- ISSN
0829-8211
- Publication type
Journal Article
- DOI
10.1139/o03-080