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- Title
Effect of creatine supplementation on measured glomerular filtration rate in postmenopausal women.
- Authors
Neves, Manoel, Jr; Gualano, Bruno; Roschel, Hamilton; Lima, Fernanda Rodrigues; Lúcia de Sá-Pinto, Ana; Seguro, Antonio Carlos; Shimizu, Maria Heloisa; Sapienza, Marcelo Tatit; Fuller, Ricardo; Lancha, Antonio Herbert, Jr; Bonfá, Eloisa
- Abstract
We aimed to investigate whether creatine supplementation affects the measured glomerular filtration rate in postmenopausal women (age, 58 ± 3 years). Subjects were randomly assigned to receive either creatine (20 g·day(-1) for 1 week and 5 g·day(-1) thereafter) or a placebo. Kidney function was assessed at baseline and after 12 weeks. [(51)Cr]EDTA clearance remained unchanged (CR-PRE: 86.16 ± 14.36 mL·min(-1) per 1.73 m(2), POST: 87.25 ± 17.60 mL·min(-1) per 1.73 m(2); PL-PRE: 85.15 ± 8.54 mL·min(-1) per 1.73 m(2), POST: 87.18 ± 9.64 mL·min(-1) per 1.73 m(2); p = 0.81). Thus, we concluded that creatine supplementation does not affect glomerular filtration rate in postmenopausal women.
- Publication
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2011, Vol 36, Issue 3, p419
- ISSN
1715-5312
- Publication type
Journal Article
- DOI
10.1139/h11-014