We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Healthy but not RSV-infected lung epithelial cells profoundly inhibit T cell activation.
- Authors
Wang, H; Su, Z; Schwarze, J
- Abstract
Respiratory viruses, including respiratory syncytial virus (RSV), can cause asthma exacerbations and bronchiolitis. Both conditions are associated with enhanced cognate immune responses and inflammation and reduced immune regulation. Lung epithelial cells (LECs) can contribute to antiviral and allergic immune responses while gut epithelial cells can inhibit effector T cell responses. A study was performed to determine whether healthy LECs regulate antigen-specific T cell responses and if this regulation is lost during RSV infection.
- Publication
Thorax, 2009, Vol 64, Issue 4, p283
- ISSN
1468-3296
- Publication type
Journal Article
- DOI
10.1136/thx.2007.094870