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- Title
Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency.
- Authors
Demeo, Dawn L; Sandhaus, Robert A; Barker, Alan F; Brantly, Mark L; Eden, Edward; McElvaney, N Gerard; Rennard, Stephen; Burchard, Esteban; Stocks, James M; Stoller, James K; Strange, Charlie; Turino, Gerard M; Campbell, Edward J; Silverman, Edwin K
- Abstract
Severe alpha(1)-antitrypsin (AAT) deficiency is an autosomal recessive genetic condition associated with an increased but variable risk for chronic obstructive pulmonary disease (COPD). A study was undertaken to assess the impact of chronic bronchitis, pneumonia, asthma and sex on the development of COPD in individuals with severe AAT deficiency.
- Publication
Thorax, 2007, Vol 62, Issue 9, p806
- ISSN
0040-6376
- Publication type
Journal Article
- DOI
10.1136/thx.2006.075846