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- Title
Functional variants of antioxidant genes in smokers with COPD and in those with normal lung function.
- Authors
Young, R P; Hopkins, R; Black, P N; Eddy, C; Wu, L; Gamble, G D; Mills, G D; Garrett, J E; Eaton, T E; Rees, M I
- Abstract
Chronic obstructive pulmonary disease (COPD) is predominantly the consequence of chronic smoking exposure, but its development may be influenced by genetic variants that affect lung remodelling, inflammation, and defence from oxidant stress. A study was undertaken to determine whether genetic variants within genes encoding the antioxidant enzymes superoxide dismutase (SOD) and catalase may be associated with the development of impaired lung function.
- Publication
Thorax, 2006, Vol 61, Issue 5, p394
- ISSN
0040-6376
- Publication type
Journal Article
- DOI
10.1136/thx.2005.048512