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- Title
Correlation of forced oscillation technique in preschool children with cystic fibrosis with pulmonary inflammation.
- Authors
Brennan, S; Hall, G L; Horak, F; Moeller, A; Pitrez, P M C; Franzmann, A; Turner, S; de Klerk, N; Franklin, P; Winfield, K R; Balding, E; Stick, S M; Sly, P D
- Abstract
Lung disease in cystic fibrosis (CF) is established in early childhood with recurrent bacterial infections and inflammation. Using spirometry, the effect of this early lung damage cannot be measured until a child is 6 years of age when some irreversible lung damage may already have occurred. Techniques for measurement of lung function in infants and young children include raised volume rapid thoracic compression (RVRTC) and low frequency forced oscillation (LFFOT). The aim of this study was to investigate the role of inflammation and infection on a population of infants and young children with CF and to determine whether lung function in this population (measured by LFFOT) is affected by early lung disease.
- Publication
Thorax, 2005, Vol 60, Issue 2, p159
- ISSN
0040-6376
- Publication type
Journal Article
- DOI
10.1136/thx.2004.026419