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- Title
Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations.
- Authors
Caramori, G; Romagnoli, M; Casolari, P; Bellettato, C; Casoni, G; Boschetto, P; Chung, K F; Barnes, P J; Adcock, I M; Ciaccia, A; Fabbri, L M; Papi, A
- Abstract
Exacerbations represent an important feature of the clinical manifestation and natural history of chronic obstructive pulmonary disease (COPD). Nuclear localisation of p65 is a signal of nuclear factor-kappaB (NF-kappaB) activation. A study was undertaken to evaluate whether NF-kappaB activation is modified in sputum cells during COPD exacerbations.
- Publication
Thorax, 2003, Vol 58, Issue 4, p348
- ISSN
0040-6376
- Publication type
Journal Article
- DOI
10.1136/thorax.58.4.348