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- Title
Effect of bradykinin on allergen induced increase in exhaled nitric oxide in asthma.
- Authors
Ricciardolo, F L M; Timmers, M C; Sont, J K; Folkerts, G; Sterk, P J
- Abstract
Exposure of patients with atopic asthma to allergens produces a long term increase in exhaled nitric oxide (FENO), probably reflecting inducible NO synthase (NOS) expression. In contrast, bradykinin (BK) rapidly reduces FENO. It is unknown whether BK suppresses increased FENO production after allergen exposure in asthma, and whether it modulates FENO via NOS inhibition.
- Publication
Thorax, 2003, Vol 58, Issue 10, p840
- ISSN
0040-6376
- Publication type
Journal Article
- DOI
10.1136/thorax.58.10.840