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- Title
Primary biliary cirrhosis: new perspectives in diagnosis and treatment.
- Authors
Prince, M I; Jones, D E
- Abstract
Primary biliary cirrhosis (PBC) is a chronic autoimmune disease characterised by cholestatic liver function tests, antimitochondrial antibodies, and abnormal liver histology. Early descriptions of a rare rapidly progressive disease no longer reflect the more indolent progress often seen today. Many patients have significant long term morbidity through symptoms such as fatigue and itch with a minority progressing to liver failure and need for transplantation. The current data on the diagnosis, clinical progression, and treatment of PBC are reviewed.
- Publication
Postgraduate medical journal, 2000, Vol 76, Issue 894, p199
- ISSN
0032-5473
- Publication type
Journal Article
- DOI
10.1136/pmj.76.894.199