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- Title
Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study.
- Authors
de Leeuw, F E; de Groot, J C; Achten, E; Oudkerk, M; Ramos, L M; Heijboer, R; Hofman, A; Jolles, J; van Gijn, J; Breteler, M M
- Abstract
White matter lesions are often seen on MR scans of elderly non-demented and demented people. They are attributed to degenerative changes of small vessels and are implicated in the pathogenesis of cognitive decline and dementia. There is evidence that especially periventricular white matter lesions are related to cognitive decline, whereas subcortical white matter lesions may be related to late onset depression. The frequency distribution of subcortical and periventricular white matter lesions according to age and sex reported.
- Publication
Journal of neurology, neurosurgery, and psychiatry, 2001, Vol 70, Issue 1, p9
- ISSN
0022-3050
- Publication type
Journal Article
- DOI
10.1136/jnnp.70.1.9