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Title
Enhanced B7 costimulatory molecule expression in inflammatory human sural nerve biopsies.
Authors
Kiefer, R; Dangond, F; Mueller, M; Toyka, K V; Hafler, D A; Hartung, H P
Abstract
To define the role of the costimulatory molecules B7-1 and B7-2 in inflammatory disorders of the peripheral nervous system. B7 molecules are essential for effective antigen presentation and may determine the differentiation of T cells into a Th-1 or Th-2 phenotype, thus modulating immune response and disease course.
Publication
Journal of neurology, neurosurgery, and psychiatry, 2000, Vol 69, Issue 3, p362