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- Title
A prospective longitudinal study of depression, cognitive decline, and physical impairments in patients with Parkinson's disease.
- Authors
Starkstein, S E; Mayberg, H S; Leiguarda, R; Preziosi, T J; Robinson, R G
- Abstract
A consecutive series of 105 patients with Parkinson's disease were examined for the presence of affective disorders, cognitive deficits, and impairments in activities of daily living (ADLs); 92 received the same evaluation 12 months after the initial examination. On the basis of the initial psychiatric findings, patients were divided into major, minor, and non-depressed groups. Patients with major depression showed a significantly greater cognitive decline, deterioration in ADLs, and further advance through the Hoehn and Yahr stages than patients with either minor depression or no depression.
- Publication
Journal of neurology, neurosurgery, and psychiatry, 1992, Vol 55, Issue 5, p377
- ISSN
0022-3050
- Publication type
Journal Article
- DOI
10.1136/jnnp.55.5.377