We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Late onset of Huntington's disease.
- Authors
Myers, R H; Sax, D S; Schoenfeld, M; Bird, E D; Wolf, P A; Vonsattel, J P; White, R F; Martin, J B
- Abstract
Twenty-five patients with late-onset Huntington's disease were studied; motor impairment appeared at age 50 years or later. The average age at onset of chorea was 57.5 years, with an average age at diagnosis of 63.1 years. Approximately 25% of persons affected by Huntington's disease exhibit late onset. A preponderance of maternal transmission was noted in late-onset Huntington's disease. The clinical features resembled those of mid-life onset Huntington's disease but progressed more slowly. Neuropathological evaluation of two cases reveal less severe neuronal atrophy than for mid-life onset disease.
- Publication
Journal of neurology, neurosurgery, and psychiatry, 1985, Vol 48, Issue 6, p530
- ISSN
0022-3050
- Publication type
Journal Article
- DOI
10.1136/jnnp.48.6.530