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- Title
Grey matter abnormality in autism spectrum disorder: an activation likelihood estimation meta-analysis study.
- Authors
Cauda, Franco; Geda, Elisabetta; Sacco, Katiuscia; D'Agata, Federico; Duca, Sergio; Geminiani, Giuliano; Keller, Roberto
- Abstract
Autism spectrum disorder (ASD) is defined on a clinical basis by impairments in social interaction, verbal and non-verbal communication, and repetitive or stereotyped behaviours. Voxel based morphometry (VBM), a technique that gives a probabilistic measure of local grey matter (GM) and white matter concentration, has been used to study ASD patients: modifications in GM volume have been found in various brain regions, such as the corpus callosum, brainstem, amygdala, hippocampus and cerebellum. However, the findings are inconsistent with respect to the specific localisation and direction of GM modifications, and no paper has attempted to statistically summarise the results available in the literature.
- Publication
Journal of neurology, neurosurgery, and psychiatry, 2011, Vol 82, Issue 12, p1304
- ISSN
1468-330X
- Publication type
Journal Article
- DOI
10.1136/jnnp.2010.239111