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- Title
Case definition for progressive multifocal leukoencephalopathy following treatment with monoclonal antibodies.
- Authors
Mentzer, Dirk; Prestel, Jürgen; Adams, Ortwin; Gold, Ralf; Hartung, Hans-Peter; Hengel, Hartmut; Kieseier, Bernd C; Ludwig, Wolf-Dieter; Keller-Stanislawski, Brigitte
- Abstract
Novel immunosuppressive/modulating therapies with monoclonal antibodies (MABs) have been associated with progressive multifocal leukoencephalopathy (PML), a potentially fatal disease of the brain caused by the JC virus. Taking the complex diagnostic testing and heterogeneous clinical presentation of PML into account, an agreed case definition for PML is a prerequisite for a thorough assessment of PML.
- Publication
Journal of neurology, neurosurgery, and psychiatry, 2012, Vol 83, Issue 9, p927
- ISSN
1468-330X
- Publication type
Journal Article
- DOI
10.1136/jnnp-2012-302478