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- Title
Evaluation of longitudinal 12 and 24 month cognitive outcomes in premanifest and early Huntington's disease.
- Authors
Stout, Julie C; Jones, Rebecca; Labuschagne, Izelle; O'Regan, Alison M; Say, Miranda J; Dumas, Eve M; Queller, Sarah; Justo, Damian; Santos, Rachelle Dar; Coleman, Allison; Hart, Ellen P; Dürr, Alexandra; Leavitt, Blair R; Roos, Raymund A; Langbehn, Doug R; Tabrizi, Sarah J; Frost, Chris
- Abstract
Deterioration of cognitive functioning is a debilitating symptom in many neurodegenerative diseases, such as Huntington's disease (HD). To date, there are no effective treatments for the cognitive problems associated with HD. Cognitive assessment outcomes will have a central role in the efforts to develop treatments to delay onset or slow the progression of the disease. The TRACK-HD study was designed to build a rational basis for the selection of cognitive outcomes for HD clinical trials.
- Publication
Journal of neurology, neurosurgery, and psychiatry, 2012, Vol 83, Issue 7, p687
- ISSN
1468-330X
- Publication type
Journal Article
- DOI
10.1136/jnnp-2011-301940