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- Title
Connexin 50 gene on human chromosome 1q21 is associated with schizophrenia in matched case control and family-based studies.
- Authors
Ni, Xingqun; Valente, Jose; Azevedo, Maria H; Pato, Michelle T; Pato, Carlos N; Kennedy, James L
- Abstract
The gap junction subunit connexin permits direct intercellular exchange of ions and molecules including glutamate, and plays an important role in the central nervous system. The connexin 40 (Cx40) and connexin 50 (Cx50) genes are located on chromosome 1q21.1, a region strongly linked with schizophrenia. These lines of evidence suggest that Cx40 and Cx50 may play a role in schizophrenia.
- Publication
Journal of medical genetics, 2007, Vol 44, Issue 8, p532
- ISSN
1468-6244
- Publication type
Research
- DOI
10.1136/jmg.2006.047944