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- Title
Additional pedigree supporting the frequent origin of XXYY from consecutive meiotic non-disjunction in paternal gametogenesis.
- Authors
Rinaldi, A; Archidiacono, N; Rocchi, M; Filippi, G
- Abstract
A 48,XXYY Sardinian patient, born to a 46,XX mother heterozygous for the Gd Mediterranean mutant, and to a 46,XY father hemizygous for the same mutant, was found to have a mosaic distribution of G6PD(+) and G6PD(-) peripheral red blood cells. The most likely interpretation of this finding is that the propositus is an additional example of an XXYY zygote derived from a consecutive meiotic non-disjunction during paternal gametogenesis.
- Publication
Journal of medical genetics, 1979, Vol 16, Issue 3, p225
- ISSN
0022-2593
- Publication type
Journal Article
- DOI
10.1136/jmg.16.3.225