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- Title
D-dimer testing: the role of the clinical laboratory in the diagnosis of pulmonary embolism.
- Authors
Mavromatis, B H; Kessler, C M
- Abstract
Pulmonary embolism is a common, yet often unsuspected and unrecognised disease associated with a high mortality. New, objective, "user friendly" and cost effective diagnostic strategies are being explored. D-dimers, the fibrinolytic degradation products of crosslinked fibrin, have emerged as the most useful of the procoagulant activity and ongoing fibrinolysis markers. D-dimer measurements are very sensitive in excluding a diagnosis of pulmonary embolism in the setting of normal values, a low clinical suspicion, and non-diagnostic lung scans. Several assays have been developed and are reviewed.
- Publication
Journal of clinical pathology, 2001, Vol 54, Issue 9, p664
- ISSN
0021-9746
- Publication type
Journal Article
- DOI
10.1136/jcp.54.9.664